News & Events

• Nanotechnology-based solutions for biomedical applications
• Revolutionary product for $2.4-billion orthodontic device market
• Regulatory approval already obtained for U.S., EU and Japan

Frankfurt / Singapore - December 18, 2009 - Nanostart AG has taken a significant ownership position in BioMers Pte Ltd, a Singapore-based medical technology company with a branch office in the U.S. The company is developing innovative new solutions for various biomedical applications with its technology.

BioMers’ has developed the world's only completely translucent braces system for orthodontic treatment. The product is set to fundamentally transform the multi-billion-dollar global market for orthodontic devices. The company also has an exciting pipeline of future products for other medical and dental applications.

Biomers is a spin-off from the renowned National University of Singapore (NUS), where the technology was invented. The technology makes use of advanced nanomaterials and fibre-reinforced polymer composite techniques to create translucent arch wires that are just as competent as metal wires.

An initial and extraordinarily promising application for this innovative product is the rapidly growing market for orthodontic braces. BioMers is the world’s only provider of orthodontic solutions that can produce aesthetic-looking archwires.

Aesthetic brackets have been available for more than 10 years. However, until now, only metal has the mechanical properties needed for the arch wires, which run along the middle of the brackets. Using nanotechnology, BioMers is able for the first time to produce translucent and thus cosmetically acceptable braces and retainers, a competitive advantage which offers BioMers the potential to be the number one choice in the orthodontics market.

The global market for orthodontic braces (archwires and brackets) and retainers (worn by patients following treatment with braces) is currently estimated at some USD 2.4 billion annually. Over the past nine years, the U.S. market for orthodontics has grown at an annual rate of approx. 7.5 percent per year, while various regions in Asia have seen orthodontics grow at double-digit rates.

The company has already received regulatory approval for its orthodontic products in the United States, the European Union and Japan. The capital invested by Nanostart will be primarily used to strengthen sales and marketing resources and to further expand the already existing network of some 40 international distribution partners.

Andreas Kröll, managing director of Nanostart Asia, remarked that "Biomers has developed, with the help of its leading-edge nanotechnology, a superb product with uniquely innovative characteristics. With the growth in demand for more esthetically pleasing solutions, the company stands to revolutionize the global market for orthodontic devices, a market which has seen relatively little innovation in recent decades. This promises to deliver high returns."

Dr. Mervyn Fathianathan, Managing Director of Biomers, added, "We are extremely pleased about bringing on board an investor like Nanostart with its uniquely successful track record in nanotechnology investments. Its international network and business experience will be of enormous help in the further development and growth of our company."

Nanostart has taken the position of Lead Investor in this new addition to its investment portfolio by way of its Nanostart Singapore Early Stage Venture Fund. The fund now owns 16 percent of Biomers.

About Nanostart:

Nanostart AG is the world’s leading nanotechnology investment company. The Frankfurt-based company provides venture capital financing for nanotechnology companies in various growth phases. It also provides the benefits of its experience and expertise to developers of financial instruments and to investors in the nanotechnology sector. For further information about the company, please visit www.nanostart.de.

Disclaimer:

This notice constitutes neither an offer to sell nor a solicitation of offers to purchase or subscribe to securities. There will be no public offering of securities of Nanostart AG in conjunction with the existing listing of its shares in the "Entry Standard" segment of the regulated unofficial market (Freiverkehr) on the Frankfurt Stock Exchange. This notice does not constitute a securities prospectus. Neither this notice nor the information contained within is intended for direct or indirect distribution within the United States of America, Canada, Australia or Japan.

Media contact:
Nanostart AG
Public Relations
Dr. Hans Joachim Dürr
Goethestrasse 26-28
D-60313 Frankfurt
Germany
phone: +49 (0)69-21 93 96 111
fax: +49 (0)69-21 93 96 122
e-mail: presse@nanostart.de

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BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.

Naples, Florida - BioMers Products, LLC wishes to report that it presented at the 25th Florida Venture Capital Conference (www.floridaventureforum.org) that took place on February 3-4, 2009, in Naples, FL. The conference is the premier venture capital conference in the south-eastern United States attracting presentations from leading technology start-up companies. In the past, presenting companies have raised $1.6 billion. This year's forum drew nearly 1,200 members from the venture community.

Randall J. Wall, the Chief Executive Officer, presented the impact BioMers' clear orthodontic wires deliver to orthodontic distributors such as TP Orthodontics, Great Lakes Orthodontics , Space Maintainers, Ortho Organizers, etc.

"BioMers was honored to be included in an impressive group of presenting start-up companies," Mr. Wall commented. "We shared how the orthodontic market is being revolutionized with the release of the world's first clear orthodontic wire (www.clear-wires.com). Patients can now opt to undergo completely aesthetic orthodontic treatment with the release of the clear arch wire and clear ASTICS® retainer."

BioMers intends to extend the application of its innovative fabrication technology to other segments of the orthodontic treatment market. An immediate target market is early teenagers undergoing orthodontic treatment. Colored wires will be released later in 2009, which appeal to this sizeable demographic segment. Mr. Wall commented, "in the clinical studies nearly all of the early teen patients wanted pink or blue colored wires, while late teenagers and adults only wanted the clear wire. With the release of colored and clear wires we target both target market segments! "

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BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.

Naples, Florida - Mr. Randall J. Wall, the CEO of BioMers Products, LLC was interviewed by Florida Trend magazine.

"The process of teeth-straightening isn't fun for anyone. But a Naples startup company is working to make wearers feel less self-conscious with a new generation of braces and retainers that have nearly invisible wires.

Ceramic brace brackets that blend in with the teeth have been around since the late 1980s, but until recently the connecting wire, called an arch wire, continued to be a metal eyesore. BioMers Products now offers a glass and polymer composite wire that almost disappears in the mouth but is strong enough to straighten teeth. "We believe that this is the next product that is going to change orthodontics," says BioMers CEO Randall Wall, who came out of retirement to launch the company. Wall introduced the first ceramic orthodontic bracket to the dental community when he was president of Unitek, then a subsidiary of Bristol-Myers Squibb...." Click here to download the full article.

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BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.

Naples, Florida - BioMers Products, LLC wishes to report that Qomel Company Ltd, a leading distributor of medical and dental products for the Saudi Arabian market has been appointed as a distributor of the BioMers Translucent Arch Wire and ASTICS® retainer.

Qomel is already a distributor of Ormco, the maker of the ICE® translucent bracket. When it is coupled with the BioMers Translucent Arch Wire and ASTICS retainer, this offers patients total aesthetic orthodontic treatment

* * *

BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.

Naples, Florida - BioMers Products, LLC wishes to report that SGS U.S. Testing Company Inc. (SGS), a world leading notified body, has granted the CE mark to the company's translucent arch wire. This allows the company and its European distributors to begin sales of the translucent wire for prolonged (greater than 30 days) indications of use.

Effective immediately, several European distributors have begun selling the translucent arch wire. This includes TP Orthodontics (Europe), Dental Depot (Holland), Smile Dental (Germany), RealKFO (Germany) and OrthoSmile (Greece). Numerous other distributors plan to begin sales in the New Year.

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BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.

Napels, Florida - BioMers Products, LLC wished to report that BioMers Pte Ltd in Singapore offers laboratory services for the fabrication of the ASTICS retainer. Doctors and patients in Singapore can opt for this aesthetic retainer instead of a traditional metal retainer. Doctors should contact the Singapore company about pricing and the various design option available.

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BioMers Products, LLC is engaged in the design and manufacture of novel polymer composite based products for biomedical applications. The company's initial focus is in the field of orthodontics. Using its patented polymer composite fabrication technology, BioMers has developed the world's only translucent orthodontic wires. Application of the wires in currently available brackets and retainers provides orthodontic patients with completely translucent braces and retainers. This alleviates the aesthetic concerns of patients undergoing orthodontic treatment. Future application areas of the fabrication technology include other dental specialities and medicine.